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Posted by / 02-Sep-2017 14:09

Green (11) gave a practical guide for analytical method validation, with a description of a set of minimum requirements for a method.

Renger and his colleagues (12) described the validation of a specific analytical procedure for the analysis of theophylline in a tablet using high-performance thin layer chromatography (HPTLC).

In response to this letter, provide your validation of laboratory instrument error codes.

Identify the specific codes that may impact product quality and the reliability of CGMP data, and provide your procedures to demonstrate how your quality unit will review, investigate, and respond to these specific codes.

This course provides a comprehensive coverage of the method development and validation requirements that are essential to progress a pharmaceutical compound, at each stage of product development.

Upon completion of this course, delegates will have learned what is necessary to develop and validate methods for drug substance and drug product to comply with international regulatory guidelines.

These include raw and intermediate chemical products, aliphatic and aromatic hydrocarbons, amines, amino acids, peptides, proteins, sugars, lipids and large pharmacologically active compounds.Scientists working with HPLC who need to further their understanding of the technique in order to develop better methods faster.Scientists who have to validate HPLC methods in accordance with current internationally-accepted guidance.Analytical methods must be validated to provide reliable data for regulatory submissions.These methods are essential for a number of purposes, including testing for QC release, testing of stability samples, testing of reference materials and to provide data to support specifications.

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HPLC can be used as qualitatively and quantitatively, for measuring purity or even as part of a clean-up procedure to prepare an analyte for additional investigation.

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